Cytidine- and guanosine-based nucleotide–lipids
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چکیده
منابع مشابه
DNAzyme-mediated catalysis with only guanosine and cytidine nucleotides
Single-stranded DNA molecules have the capacity to adopt catalytically active structures known as DNAzymes, although the fundamental limits of this ability have not been determined. Starting with a parent DNAzyme composed of all four types of standard nucleotides, we conducted a search of the surrounding sequence space to identify functional derivatives with catalytic cores composed of only thr...
متن کاملNuclear magnetic resonance study of the interactions of guanosine and cytidine in dimethyl sulfoxide.
Guanosine forms hydrogen-bonded dimers in DMSO. The equilibrium constant for dimer formation is 0.18 l./mol at 32”, and there is no evidence of higher order aggregates. The structure of the dimer is probably similar to the hydrogen bonding thought to occur in guanylic acid gels but it is not possible from our results to assign a unique hydrogen-bonding scheme. Cytidine and 1-methylguanosine sho...
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Nuclei isolated from rat liver, when incubated with methyl-labeled S-adenosylmethionine, incorporated label into 2'-O-methyladenosine, 2'-O-methylguanosine, 2'-O-methyluridine, and 2'-O-methylcytidine of endogenous nuclear RNA. Addition of ribosomal RNA from wheat germ to the reaction markedly stimulated 2'-O-methylation of total RNA. The relative incorporation of label into the four different ...
متن کاملCytidine-phosphate-guanosine oligodeoxynucleotides and interferon-alpha-expressing tumor cells effectively induce dendritic cell maturation in vitro.
BACKGROUND Dendritic cells (DCs) play an important role in immune response and cytidine-phosphate-guanosine (CpG) oligodeoxynucleotides (ODN) as well as interferon (IFN)-alpha have been proven to induce DC maturation. In this study, the synergistic effects of CpG-ODN and IFN-alpha on DC maturation were evaluated. MATERIALS AND METHODS Surface molecules on DCs and the stimulatory responses of ...
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Strain GS, a gram-negative motile bacterium isolated from soil, synthesizes two polysaccharides. The synthesis of a uranic acid-containing polysaccharide is derepressed by high concentrations of Na2SOd, while the synthesis of the polysaccharide containing equal quantities of n-rhamnose and n-talomethylose is repressed by NazS01 (1, 2). L-F’ucose and L-rhamnose are the methylpentoses commonly fo...
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2018
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c8ob01023d